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Apigenin inhibits in vitro and in vivo tumorigenesis in cisplatin-resistant colon cancer cells by inducing autophagy, programmed cell death and targeting m-TOR/PI3K/Akt signalling pathway

The best-known functional ADH variant is the rs1229984 polymorphism (Arg48His), associated with the ADH1B*2 allele, which produces an enzyme with higher catalytic activity for converting ethanol to acetaldehyde